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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1985-8-30
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pubmed:abstractText |
The risk of malignant mesothelioma associated with low-level asbestos exposure is an important unresolved issue today. We have analyzed the asbestos fiber concentration in lung tissue from 14 cases of malignant mesothelioma and 28 case-matched controls by scanning electron microscopy. The cases represent 86% of all mesotheliomas recorded by the Cancer Registry of Norway from the county of Hordaland between 1970 and 1979. Based on 1 million fibers per g of dried tissue as an indicator of cumulated asbestos exposure, the odds ratio (relative risk) was 8.5 (95% confidence limits, 2.3-31.1). Assuming that the risk of malignant mesothelioma is related to mineral fiber concentration in lung tissue, it is concluded that a fiber concentration exceeding 1 million fibers per g of dried tissue is associated with an increased risk of malignant mesothelioma. Furthermore, the results are consistent with a no-threshold response.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1089-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4016698-Adult,
pubmed-meshheading:4016698-Aged,
pubmed-meshheading:4016698-Asbestos,
pubmed-meshheading:4016698-Female,
pubmed-meshheading:4016698-Humans,
pubmed-meshheading:4016698-Lung,
pubmed-meshheading:4016698-Male,
pubmed-meshheading:4016698-Mesothelioma,
pubmed-meshheading:4016698-Middle Aged,
pubmed-meshheading:4016698-Norway,
pubmed-meshheading:4016698-Occupational Diseases,
pubmed-meshheading:4016698-Pleural Neoplasms,
pubmed-meshheading:4016698-Probability,
pubmed-meshheading:4016698-Risk
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pubmed:year |
1985
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pubmed:articleTitle |
Fiber concentration in lung tissue of patients with malignant mesothelioma. A case-control study.
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pubmed:publicationType |
Journal Article
|