Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-9-24
pubmed:abstractText
The roles of posterior bulging of the interventricular septum (septal bulge) and of systolic septal mitral apposition in patients with simple transposition of the great arteries are not known. Cross sectional echocardiograms of 40 such patients were reviewed (after exclusion of those with fixed left ventricular outflow tract obstruction) and haemodynamic findings were compared with long and short axis measurements within the left ventricle. There was no significant correlation between the degree of septal bulge and systolic gradient across the left ventricular outflow tract, but septal bulge correlated weakly with systolic right ventricular pressure and inversely with pulmonary arteriolar resistance index. Systolic left ventricular outflow gradient was inversely related to the minimum systolic distance between the anterior mitral leaflet and interventricular septum. No patients without complete systolic apposition of the anterior mitral leaflet and interventricular septum had a left ventricular outflow gradient greater than 20 mm Hg. Conversely, even when cross sectional echocardiography showed apparently total obstruction of the left ventricular outflow tract at some time in systole there was often no significant gradient detected during haemodynamic study. In the short axis cuts closeness of the papillary muscles to the interventricular septum or to each other was unrelated to systolic gradient. This study shows that (a) cross sectional echocardiography can identify fixed obstruction of the left ventricular outflow tract in simple transposition of the great arteries; (b) the degree of septal bulge, unless complicated by fibrous thickening of the anterior mitral leaflet and interventricular septum, is unrelated to the gradient across the left ventricular outflow tract; (c) the absence of systolic septal/mitral apposition excludes a significant gradient at that site across the left ventricular outflow tract; and (d) papillary muscle geometry is unrelated to dynamic gradients across the left ventricular outflow in this condition.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-1169132, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-4451592, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-453050, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-4719171, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-4780874, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-491726, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-626131, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-6449522, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-6616771, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-6702690, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-6731308, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-6851056, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-696567, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7081078, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-709764, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7189807, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7200721, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7201133, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7236458, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-7236462, http://linkedlifedata.com/resource/pubmed/commentcorrection/4015930-776439
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0007-0769
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Left ventricular outflow tract obstruction in complete transposition of the great arteries with intact ventricular septum. A cross sectional echocardiography study.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't