Linked Life Data

4014500

Source:http://linkedlifedata.com/resource/pubmed/id/4014500

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 2
pubmed:dateCreated
1985-8-13
pubmed:abstractText
The location of spinal pathways mediating the respiratory modulation of sympathetic nerve activity was determined. Left inferior cardiac sympathetic, phrenic, and external intercostal (T1) nerve activities were recorded in 16 alpha-chloralose-anesthetized, vagotomized, paralyzed cats. Baroreceptor reflex activation of sympathetic activity was tested by bilateral carotid occlusion. Eight cats received C6-C7 level ventral spinal cord hemisections followed by cumulative lesions leading to total spinal cord transection. Eight other cats received C6-C7 level dorsolateral funiculus (DLF) lesions followed by dorsal spinal cord hemisection and subsequent spinal cord transection. The respiratory modulation of sympathetic activity was quantitatively assessed using respiration-triggered computer summation of sympathetic activity. Ventral hemisection had no significant effect on the respiratory modulation of sympathetic activity or bilateral carotid occlusion responses. In contrast, bilateral DLF lesions eliminated both the respiratory modulation and bilateral carotid occlusion responses. Unilateral disruption of DLF pathways ipsilateral to the recorded sympathetic nerve indicated spinal level decussations. Thus bilaterally descending DLF pathways with spinal level decussations mediate the respiratory modulation of sympathetic activity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
249
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R91-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Spinal pathways mediating respiratory influences on sympathetic nerves.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.