Linked Life Data

4012264

Source:http://linkedlifedata.com/resource/pubmed/id/4012264

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-8-16
pubmed:abstractText
The p.d. of the rat seminiferous tubules was 4.75 +/- 1.39 mV (lumen negative) at 35 degrees C and varied linearly with temperatures from 26 to 40 degrees C. A depolarization of the seminiferous tubules was found in the rats administered with gossypol at the dosage of 30 mg/kg body weight for 3 weeks, the p.d. lowered to 3.63 +/- 0.79 mV at 35 degrees C and was independent of the changes of seminiferous tubules temperature. In the 5-week-gossypol-treatment group, the tracer penetrated not only the myoid cell layer, but also went beyond the tight junction complexes between Sertoli cells. The lanthanum appeared in the cleft surrounding spermatogonia. In the 8-week-gossypol-treatment group, the lanthanum was found in the adluminal compartment. It indicates that gossypol can cause a dysfunction of the Sertoli cells and blood-testis barrier and disturb a good physiological environment for the developing spermatocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0253-5823
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
402-9
pubmed:dateRevised
2009-5-29
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Effect of gossypol on the potential difference of rat seminiferous tubules.
pubmed:publicationType
Journal Article