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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1985-7-29
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pubmed:abstractText |
A collaborative study was carried out to assess the suitability of a preparation to serve as the International Standard for Dermatophagoides pteronyssinus (house dust mite) extract. The proposed international standard of D. pteronyssinus, two additional freeze-dried extracts, and a commercially available skin testing solution were tested in the study. Nineteen laboratories in 11 different countries participated. The assay methods used included RAST inhibition, crossed immunoelectrophoresis/crossed radioimmunoelectrophoresis, isoelectric focusing, quantitative skin testing, and various other methods for assessing total allergenic activity. In addition, six laboratories measured the quantity of antigen P1, and three laboratories measured antigen DpX in each of the preparations. On the basis of the results from this study, the World Health Organization established the preparation as the International Standard for D. pteronyssinus extract with an assigned unitage of 100,000 IU per ampule. The units refer both to the total allergenic activity of the ampule and to that of the individual allergens, such as P1 and DpX.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Dermatophagoides,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/Dust,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Extracts
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0091-6749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
676-86
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:4008796-Allergens,
pubmed-meshheading:4008796-Animals,
pubmed-meshheading:4008796-Antigens, Dermatophagoides,
pubmed-meshheading:4008796-Cell Extracts,
pubmed-meshheading:4008796-Dose-Response Relationship, Immunologic,
pubmed-meshheading:4008796-Drug Stability,
pubmed-meshheading:4008796-Dust,
pubmed-meshheading:4008796-Freeze Drying,
pubmed-meshheading:4008796-Humans,
pubmed-meshheading:4008796-Immunoelectrophoresis, Two-Dimensional,
pubmed-meshheading:4008796-International Cooperation,
pubmed-meshheading:4008796-Isoelectric Focusing,
pubmed-meshheading:4008796-Mites,
pubmed-meshheading:4008796-Radioallergosorbent Test,
pubmed-meshheading:4008796-Tissue Extracts
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pubmed:year |
1985
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pubmed:articleTitle |
A collaborative study on the first international standard of Dermatophagoides pteronyssinus (house dust mite) extract.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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