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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-8-20
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pubmed:abstractText |
Light and electron microscopic observations on the structure of epiphyseal cartilages in the cmd/cmd mice, which had genetically failed to synthesize cartilage-characteristic proteoglycan but were normal in type II collagen synthesis, showed apparent abnormalities of collagen fibrils: e.g. increase in the diameter, appearance of periodic banding patterns and bundle-formation of collagen fibrils. These findings suggest that cartilage-characteristic proteoglycan normally limits the lateral growth of collagen fibrils and affects collagen fibrillogenesis in vivo.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0174-173X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
137-47
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:4006426-Animals,
pubmed-meshheading:4006426-Collagen,
pubmed-meshheading:4006426-Dwarfism,
pubmed-meshheading:4006426-Extracellular Matrix,
pubmed-meshheading:4006426-Growth Plate,
pubmed-meshheading:4006426-Mice,
pubmed-meshheading:4006426-Mice, Mutant Strains,
pubmed-meshheading:4006426-Microscopy, Electron,
pubmed-meshheading:4006426-Microscopy, Electron, Scanning,
pubmed-meshheading:4006426-Proteoglycans,
pubmed-meshheading:4006426-Rodent Diseases
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pubmed:year |
1985
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pubmed:articleTitle |
Abnormal collagen fibrillogenesis in epiphyseal cartilage of CMD (cartilage matrix deficiency) mouse.
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pubmed:publicationType |
Journal Article
|