Linked Life Data

4003546

Source:http://linkedlifedata.com/resource/pubmed/id/4003546

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 1
pubmed:dateCreated
1985-7-24
pubmed:abstractText
Surface hydrophobicity of the luminal lining of the canine stomach has been studied as a very convenient means of following the adsorbed monolayer of surfactant believed to provide the gastric mucosal barrier. Hydrophobicity has been measured as the contact angle (theta) produced when a drop of saline is placed upon the surface. theta was found to decrease from 82 to 62 degrees upon 50% linear extension of samples of oxyntic mucosa from 10 dogs. When the phospholipid believed to cause the hydrophobicity was absorbed to glass slides, the contact angle was found to decrease with lower surface concentration. Thinning or "crazing" of the absorbed surfactant monolayer imparting the very hydrophobic nature of the luminal lining is discussed as a possible reason why ulcers tend to form at the crests of the folds, i.e., at points where the surface has been stretched and the monolayer disrupted.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
248
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
G643-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Gastric mucosal barrier: hydrophobicity of stretched stomach lining.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.