Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-7-24
pubmed:abstractText
Coronary diameters and central hemodynamics were measured in 22 patients with stable coronary artery disease before and after 20 mg of intravenous diltiazem. Coronary diameters from high quality biplane coronary angiograms were calculated as mean values after caliper measurements of identical segments. Measurements were made in angiographically normal and abnormal proximal, middle and distal vessel segments. Central hemodynamics showed a significant decrease for heart rate, mean aortic pressure and peripheral resistance (p less than 0.001). Coronary diameters increased between 2 and 16% (proximal or distal segments). Diameter increases were statistically significant for all segments (p less than 0.001) except for proximal atherosclerotic segments. These hemodynamic and diameter changes were seen after 5, 10 and 20 minutes. Conclusion: Intravenous diltiazem shows an acute coronary dilative effect in patients with stable coronary artery disease. This effect is regarded as one of the essential antianginal actions of the drug.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0300-5860
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
238-44
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Dilatation of epicardial coronary vessels by intravenous diltiazem in patients with coronary heart disease].
pubmed:publicationType
Journal Article, English Abstract