Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1985-7-2
pubmed:abstractText
To clarify the mechanism of the elimination of radioactivity after administration of radioiodinated heptadecanoic acid, dogs with and without coronary occlusion were studied. In myocardial tissue samples of normal and ischemic myocardium, the proportions of free radioiodide, radioiodinated heptadecanoic acid, and radioiodinated lipids were determined. Five minutes after intravenous injection of heptadecanoic acid 69% of the radioactivity was present as free iodine, 7% as unaltered heptadecanoic acid, and 24% as lipids. Even in ischemic myocardium 41% was free iodine and 47% lipids. After 2 h free iodine decreased to 48% and lipids increased to 44%. These results indicate that beta-oxidation is not the rate-limiting step in the elimination rate of heptadecanoic acid.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0340-6997
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
118-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The myocardial elimination rate of radioiodinated heptadecanoic acid.
pubmed:publicationType
Journal Article, Comparative Study