Linked Life Data

3996015

Source:http://linkedlifedata.com/resource/pubmed/id/3996015

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-7-25
pubmed:abstractText
Surface cooling as an adjunct to cardiopulmonary bypass, core cooling, and circulatory arrest has been effectively used to produce more homogeneous cooling and better tissue preservation. A previous study, using pigs with newly created aortopulmonary shunts, revealed a redistribution of blood flow away from the kidneys and viscera during surface cooling that did not occur in normal pigs. The present study tests the hypothesis that pigs with mature aortopulmonary shunts behave in a similar manner. Group I (N = 7, unshunted pigs) and Group II (N = 7, shunted pigs) underwent surface cooling and blood flow distribution measurements by microspheres at 37, 32, 28, and 25 degrees C. Both Groups I and II experienced a decrease in cardiac output with hypothermia. Group II had decreased absolute tissue flow to the viscera, kidneys, muscle, and skin at 37 degrees C compared with Group I, even before the onset of hypothermia. During hypothermia, Group I experienced a decrease in all tissue flows, but Group II had a decrease only in visceral and renal flows at 25 degrees C. Blood flow distribution, as a percentage of cardiac output, showed little change (decrease only in skin) in Group I with hypothermia. In Group II, however, a maldistribution of cardiac output developed resulting in decreased percentage of cardiac output to the kidneys and viscera and an increased percentage of cardiac output to the lungs that was confirmed by an increase in the Qp/Qs ratio.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0011-2240
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The effect of surface cooling on blood flow distribution in infant pigs with mature left to right shunts.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't