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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-7-11
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pubmed:abstractText |
The results of cytogenetic analyses of bone marrow and peripheral blood cells in a 67-year-old male with chronic eosinophilic leukemia (EL) are described. Although the patient showed leukocytosis with marked eosinophilia, initial chromosome findings in bone marrow revealed a normal male karyotype. Seven months later, more than 80% of bone marrow cells had a hyperdiploid karyotype (48,XY, +7, +8), the remaining cells being normal. Seven weeks later, the identical abnormal karyotype was observed in about 30% of banded metaphases of stimulated peripheral blood cells. No mitoses were found in unstimulated cultures. No Ph chromosome was observed. So far, trisomy 8 has been described for only two cases of EL, whereas trisomy 7 has never been observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-64
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3995497-Aged,
pubmed-meshheading:3995497-Chromosome Banding,
pubmed-meshheading:3995497-Chromosomes, Human, 6-12 and X,
pubmed-meshheading:3995497-Chronic Disease,
pubmed-meshheading:3995497-Eosinophils,
pubmed-meshheading:3995497-Humans,
pubmed-meshheading:3995497-Karyotyping,
pubmed-meshheading:3995497-Leukemia,
pubmed-meshheading:3995497-Leukocyte Count,
pubmed-meshheading:3995497-Male,
pubmed-meshheading:3995497-Polyploidy,
pubmed-meshheading:3995497-Trisomy
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pubmed:year |
1985
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pubmed:articleTitle |
Trisomy 7 and 8 in Ph-negative chronic eosinophilic leukemia.
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pubmed:publicationType |
Journal Article,
Case Reports
|