Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-5-29
pubmed:abstractText
Sperm without acrosome of two males--spouses of infertile marriages--were studied. No acrosome could be identified in the Papanicolaou stained smears of either patient. Electron microscopy study confirmed the absence of acrosome and post-acrosomal sheath. The physical and functional integrity of the sperm membrane was determined by vital staining technique (72% unstained) and hypoosmotic stress test (69% swollen). Acrosin assay showed a five-fold decrease, and proacrosin values were almost eight-fold lower than the normal values. Nonzymogen acrosin level was normal. Zone-free hamster oocytes were not penetrated by the acrosomeless sperm showing 46% progressive motility, but postcoital tests in both female spouses showed active sperm. The results would indicate that the sperm devoid of acrosome may be considered as a primary cause of male infertility.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0303-4569
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Acrosomeless sperm. A cause of primary male infertility.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't