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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-5-29
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pubmed:abstractText |
Sperm without acrosome of two males--spouses of infertile marriages--were studied. No acrosome could be identified in the Papanicolaou stained smears of either patient. Electron microscopy study confirmed the absence of acrosome and post-acrosomal sheath. The physical and functional integrity of the sperm membrane was determined by vital staining technique (72% unstained) and hypoosmotic stress test (69% swollen). Acrosin assay showed a five-fold decrease, and proacrosin values were almost eight-fold lower than the normal values. Nonzymogen acrosin level was normal. Zone-free hamster oocytes were not penetrated by the acrosomeless sperm showing 46% progressive motility, but postcoital tests in both female spouses showed active sperm. The results would indicate that the sperm devoid of acrosome may be considered as a primary cause of male infertility.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0303-4569
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3994001-Acrosin,
pubmed-meshheading:3994001-Acrosome,
pubmed-meshheading:3994001-Adult,
pubmed-meshheading:3994001-Animals,
pubmed-meshheading:3994001-Cricetinae,
pubmed-meshheading:3994001-Female,
pubmed-meshheading:3994001-Humans,
pubmed-meshheading:3994001-Infertility, Male,
pubmed-meshheading:3994001-Male,
pubmed-meshheading:3994001-Sperm-Ovum Interactions,
pubmed-meshheading:3994001-Spermatozoa,
pubmed-meshheading:3994001-Testis
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pubmed:articleTitle |
Acrosomeless sperm. A cause of primary male infertility.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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