Linked Life Data

3991424

Source:http://linkedlifedata.com/resource/pubmed/id/3991424

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-6-12
pubmed:abstractText
This experiment, involving 320 chicks, was conducted to determine the effects of dietary cholesterol, restricted caloric intake, and genetic lines on cholesterol metabolism in the bird. The two lines of chicks studied had been divergently selected for oxygen consumption and had been shown to differ significantly (P less than .01) in weight gain and carcass lipid deposition. The dietary treatments, administered for a 2-week period, consisted of two levels of dietary cholesterol (none and supplemented) for each of two levels of energy (ad libitum and restricted). At the end of this 2-week period, the birds were injected intravenously with 1-14C-acetate and their livers removed 4 hr later. Hepatic cholesterol and lipid synthesis were measured by the uptake of acetate. Added dietary cholesterol significantly (P less than .01) decreased hepatic cholesterol synthesis, lipid synthesis, and specific activity of hepatic cholesterol but increased plasma and liver cholesterol. However, the elevation in plasma and liver cholesterol represented only .9 and 1.8% respectively, of the increase in total intake of dietary cholesterol. Metabolizable energy of diets fed ad libitum was also significantly (P less than .01) reduced with supplemented dietary cholesterol. A significant (P less than .01) difference in body weight was present between the two lines, with low oxygen consuming (LOC) birds exhibiting heavier body weights than high oxygen consuming (HOC) birds. A significant interaction between line and energy intake (P less than .05) was present for hepatic cholesterol levels; LOC birds exhibited higher levels of hepatic cholesterol than HOC birds when both groups were fed at restricted levels.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0032-5791
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
502-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The effect of dietary cholesterol, energy intake, and oxygen consumption on cholesterol metabolism in the chick.
pubmed:publicationType
Journal Article