Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-6-7
pubmed:abstractText
Castration of the male lizard Amphibolurus ornatus results in atrophy of the femoral glands. The amount of secretion collected from glands decreased from (mean +/- SE) 136.6 +/- 13.0 micrograms/g body wt prior to castration to 102.7 +/- 14.6 micrograms/g body wt 28 days after castration (P less than 0.001). Over the same period the secretion from a group of intact males increased. Biosynthesis of steroids by testicular tissue from A. ornatus was studied in vitro using [4-14C]progesterone as substrate. A single androgen, probably testosterone, was isolated. Daily injections for 28 days of 1 microgram/g body wt of testosterone propionate (TP) and 5 alpha-dihydrotestosterone (DHT) stimulated femoral gland secretion in castrated males (TP, 201.8 +/- 21.5 micrograms/g body wt; DHT, 142.8 +/- 16.0 micrograms/g body wt). The glands of animals receiving injection medium only remained atrophic. Identical regimes of TP and DHT also stimulated femoral gland secretion in intact females from which no exudate could initially be collected. These data are consistent with the hypothesis that lizard femoral glands are androgen-dependent secondary sex characters.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
371-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Hormonal control of femoral gland secretion in the lizard, Amphibolurus ornatus.
pubmed:publicationType
Journal Article