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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1985-6-19
|
| pubmed:abstractText |
The effect of ten daily injections of saline or d-lysergic acid diethylamide (LSD) (260 micrograms/kg i.p.) on serotonin1 (5-hydroxytryptamine1, 5-HT1) and 5-HT2 receptor binding was determined in brain membranes from rats killed 24 h after the last injection. [3H]LSD (3.0 nM) was used with either 30.0 nM 5-HT or 70.0 nM cinanserin to estimate 5-HT1 and 5-HT2 receptors, respectively. LSD administration decreased 5-HT2 binding in cortex, striatum, hippocampus, and diencephalon/midbrain without altering 5-HT1 or total specific binding.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0014-2999
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
12
|
| pubmed:volume |
109
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
421-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3987809-Animals,
pubmed-meshheading:3987809-Brain,
pubmed-meshheading:3987809-Cerebral Cortex,
pubmed-meshheading:3987809-Corpus Striatum,
pubmed-meshheading:3987809-Drug Tolerance,
pubmed-meshheading:3987809-Hippocampus,
pubmed-meshheading:3987809-Lysergic Acid Diethylamide,
pubmed-meshheading:3987809-Male,
pubmed-meshheading:3987809-Rats,
pubmed-meshheading:3987809-Rats, Inbred Strains,
pubmed-meshheading:3987809-Receptors, Serotonin
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Daily LSD administration selectively decreases serotonin2 receptor binding in rat brain.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|