Linked Life Data

3983217

Source:http://linkedlifedata.com/resource/pubmed/id/3983217

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-5-9
pubmed:abstractText
Two experiments were performed to test the hypotheses that cholinergic activity of the caudate nucleus (CN) is involved in the acquisition and in the maintenance of passive avoidance behavior. Rats were trained, in one trial, to avoid one of two compartments of a conditioning box and retention of the task was measured 24 hours later. Several doses of atropine were injected into the CN of independent groups of animals. In Experiment 1 the atropine was injected 2 minutes after training and in Experiment 2 it was injected 6 minutes before retention testing. In both cases a dose-dependent retention deficit was found. These results indicate that striatal cholinergic activity is indeed involved in the processes that mediate passive avoidance conditioning.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Injections of atropine into the caudate nucleus impair the acquisition and the maintenance of passive avoidance.
pubmed:publicationType
Journal Article