Linked Life Data

3982434

Source:http://linkedlifedata.com/resource/pubmed/id/3982434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-5-17
pubmed:abstractText
The radiosensitivity of murine teratocarcinoma cells was investigated. Our findings are as follows: (1) the undifferentiated teratocarcinoma cells are 3 times more sensitive to UV than their differentiated counterpart and BALB/3T3 cells; (2) X-ray sensitivity of the undifferentiated cells is comparable to that of BALB/3T3 cells; (3) post-irradiation treatment with caffeine strongly sensitizes a fraction of the undifferentiated cells to UV and X-rays resulting in biphasic survival curves of the cells; (4) high UV sensitivity and hyper-sensitization by caffeine is lost upon differentiation of the cells. Possible mechanisms for the unusually high sensitivity of undifferentiated teratocarcinoma cells to radiation and post-irradiation treatment with caffeine will be discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
145
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-200
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
High sensitivity of murine teratocarcinoma cells to UV radiation and the effect of post-irradiation treatment with caffeine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't