Linked Life Data

3981260

Source:http://linkedlifedata.com/resource/pubmed/id/3981260

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-5-16
pubmed:abstractText
We studied plasma lipoprotein and hormone concentrations in rhesus monkeys that had consumed either a low protein (3.8% of kilocalories) or a control protein (13.9%) purified diet since birth (6-10 yr before the beginning of this experiment) in order to test the hypothesis that chronic protein deficiency could influence plasma lipoproteins through an effect on the hepatic metabolism of gonadal or thyroid hormones. Protein-deficient monkeys had greater plasma concentrations of very low density lipoproteins (VLDL) plus high density lipoproteins (HDL) than controls. They also had lower serum albumin and greater alkaline phosphatase levels than the controls. Plasma thyroxine (T4) and free T4 concentrations were lower and the triiodothyronine (T3) levels tended to be greater in the protein-deficient group than in controls. This effect was apparent at two widely different levels of dietary iodide. Plasma T3 concentrations were elevated in other adult rhesus monkeys that were fed the low protein diet for only 6 wk. Monkeys injected with estradiol benzoate (100 micrograms/kg body weight) for 4 d had a marked reduction of VLDL concentrations. VLDL triglycerides were depressed more and plasma estrone levels were greater in deficient monkeys than in controls at 24 h after the last injection. In the control monkeys the T3 level rose and T4/T3 fell in response to estrogen injections, whereas the deficient monkeys did not respond.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-35
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Dietary protein effects on lipoproteins and on sex and thyroid hormones in blood of rhesus monkeys.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.