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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-10
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pubmed:abstractText |
One- or two-gram doses of ceftriaxone were administered intravenously to 30 patients before cataract extraction. With the 1-g dose, mean aqueous humor concentrations of 0.93 and 0.88 microgram/mL were found at approximately 2 and 12 hours after administration, respectively. With the 2-g dose, a mean level of 2.47 micrograms/mL was observed at two hours; levels of more than 2 micrograms/mL were found in two patients 13 hours after administration. Both the 1- and 2-g doses thus produce aqueous humor levels many times higher than the minimum inhibitory concentration of ceftriaxone for 90% of most Enterobacteriaceae, excluding Pseudomonas. Concentrations adequate for Staphylococcus aureus and Staphylococcus epidermidis were not, however, obtained.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0003-9950
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3977680-Adult,
pubmed-meshheading:3977680-Aqueous Humor,
pubmed-meshheading:3977680-Cataract Extraction,
pubmed-meshheading:3977680-Cefotaxime,
pubmed-meshheading:3977680-Ceftriaxone,
pubmed-meshheading:3977680-Enterobacteriaceae,
pubmed-meshheading:3977680-Female,
pubmed-meshheading:3977680-Humans,
pubmed-meshheading:3977680-Male,
pubmed-meshheading:3977680-Microbial Sensitivity Tests,
pubmed-meshheading:3977680-Premedication
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pubmed:year |
1985
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pubmed:articleTitle |
Ceftriaxone. A new cephalosporin with aqueous humor levels effective against enterobacteriaceae.
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pubmed:publicationType |
Journal Article
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