|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1985-3-27
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|
pubmed:abstractText |
The exact role of the heparin-releasable hepatic endothelial lipase has remained controversial. It has been suggested that it acts in concert with lipoprotein lipase in the step-wise delipidation of triglyceride-rich lipoproteins. On the other hand, there is evidence indicating that high density lipoprotein2 is the preferred substrate for hepatic lipase. Here, it is shown that a moderate (27%) suppression of hepatic lipase activity by estrogen did not impair removal of 3H-labeled very low density lipoproteins (VLDL) triglycerides, suggesting that this enzyme is not a major regulator of VLDL catabolism under physiological circumstances.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0014-5793
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
11
|
|
pubmed:volume |
181
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
160-4
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:3972103-Endothelium,
pubmed-meshheading:3972103-Estradiol,
pubmed-meshheading:3972103-Female,
pubmed-meshheading:3972103-Humans,
pubmed-meshheading:3972103-Kinetics,
pubmed-meshheading:3972103-Lipase,
pubmed-meshheading:3972103-Lipoprotein Lipase,
pubmed-meshheading:3972103-Lipoproteins, VLDL,
pubmed-meshheading:3972103-Liver,
pubmed-meshheading:3972103-Middle Aged,
pubmed-meshheading:3972103-Triglycerides
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|
pubmed:year |
1985
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|
pubmed:articleTitle |
Very low density lipoprotein triglyceride kinetics during hepatic lipase suppression by estrogen. Studies on the physiological role of hepatic endothelial lipase.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
