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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1985-4-19
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pubmed:abstractText |
The influence of phenobarbital and TCDD pretreatment on the formation and biliary excretion of TCDD-metabolites following single doses of 3H-TCDD was investigated. Without pretreatment, 24.5% of the absorbed 3H-TCDD dose was excreted in the bile within 110 h. Phenobarbital did not influence this rate, whereas a single dose of 10 micrograms of unlabeled TCDD/kg b.wt nine days earlier resulted in a doubling of the amount of radioactive material eliminated in the bile (47.4%).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
0014-4754
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
376-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3972084-Animals,
pubmed-meshheading:3972084-Bile,
pubmed-meshheading:3972084-Dioxins,
pubmed-meshheading:3972084-Dogs,
pubmed-meshheading:3972084-Feces,
pubmed-meshheading:3972084-Intestinal Absorption,
pubmed-meshheading:3972084-Kinetics,
pubmed-meshheading:3972084-Liver,
pubmed-meshheading:3972084-Male,
pubmed-meshheading:3972084-Phenobarbital,
pubmed-meshheading:3972084-Tetrachlorodibenzodioxin
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pubmed:year |
1985
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pubmed:articleTitle |
Influence of phenobarbital and TCDD on the hepatic metabolism of TCDD in the dog.
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pubmed:publicationType |
Journal Article
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