Linked Life Data

3971159

Source:http://linkedlifedata.com/resource/pubmed/id/3971159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-4-8
pubmed:abstractText
The response characteristics of neurons at the origin of the postsynaptic dorsal column (PSDC) pathway were determined in unanesthetized, decerebrated, spinalized rats. Sixty-four percent of PSDC neurons responded only to innocuous mechanical stimuli. Thirty-six percent responded to innocuous stimuli but were more powerfully activated by noxious pinch. Ninety-three percent of the tested PSDC neurons were not activated by any of several intensities of sustained, repeated noxious heating of their receptive fields. The failure of pinch-responsive PSDC cells to respond to thermal stimulation, even in sensitized skin, suggests that they do not receive a functionally significant input from C polymodal nociceptors, heat nociceptors, or mechanical-heat nociceptors. We conclude, therefore, that the postsynaptic dorsal column pathway is not importantly involved in nociception in the rat.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
326
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
347-56
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Postsynaptic dorsal column pathway of the rat. II. Evidence against an important role in nociception.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.