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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-4
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pubmed:abstractText |
In serum deprived NIH 3T3 mouse cells the diuretic-sensitive transport system performs K+ self-exchange. The addition of serum which stimulates cell proliferation induces a net influx of K+, carried out by the diuretic-sensitive transport system. Thus, serum growth factors appear to induce a change in the mechanism of action of the diuretic-sensitive transporter from K+ self-exchange to an uphill transport pumping K+ into the cell. I propose here that this uphill uptake of K+ contributes to the increase of intracellular K+ content, found in the early G1 phase of the cell cycle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
813
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-4
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3970915-Animals,
pubmed-meshheading:3970915-Biological Transport,
pubmed-meshheading:3970915-Blood,
pubmed-meshheading:3970915-Cell Division,
pubmed-meshheading:3970915-Cell Line,
pubmed-meshheading:3970915-Fibroblasts,
pubmed-meshheading:3970915-Furosemide,
pubmed-meshheading:3970915-Interphase,
pubmed-meshheading:3970915-Mice,
pubmed-meshheading:3970915-Potassium
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pubmed:year |
1985
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pubmed:articleTitle |
Serum-induced net K+ influx performed by the diuretic-sensitive transport system in quiescent NIH 3T3 mouse fibroblasts.
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pubmed:publicationType |
Journal Article
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