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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1985-3-20
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pubmed:abstractText |
Mouse IFN inhibited the development of transformed foci in NIH 3T3 cultures transfected with the viral Ha-MuSV(ras) and Mo-MuSV(mos) oncogenes, or with the human bladder carcinoma ras EJ/T24 DNA. IFN treatment five or seven days after transfection was still effective in inhibiting the oncogenic transformation, but did not inhibit significantly the biochemical transformation induced by pSV2-neo or Ecogpt DNA, so that inhibition of ras-induced transformation was not a result of a general effect on the transfection process. Treatment with IFN did not alter the expression of ras EJ/T24 DNA after the transformed phenotype had been established.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
509-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3970704-Animals,
pubmed-meshheading:3970704-Cell Line,
pubmed-meshheading:3970704-Cell Transformation, Neoplastic,
pubmed-meshheading:3970704-Harvey murine sarcoma virus,
pubmed-meshheading:3970704-Humans,
pubmed-meshheading:3970704-Interferon Type I,
pubmed-meshheading:3970704-Mice,
pubmed-meshheading:3970704-Oncogenes,
pubmed-meshheading:3970704-Operon,
pubmed-meshheading:3970704-Phenotype,
pubmed-meshheading:3970704-Transfection,
pubmed-meshheading:3970704-Urinary Bladder Neoplasms
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pubmed:year |
1985
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pubmed:articleTitle |
Development of transformed phenotype induced by a human ras oncogene is inhibited by interferon.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|