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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1985-3-7
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pubmed:abstractText |
Oral administration of Prudhoe Bay crude or Hibernia crude to nestling herring gulls increased the hepatic cytochrome P-450 content 4-fold. Concomitantly, there was an increase in various mixed-function oxidase and phase II enzyme activities. 7-Ethoxyresorufin O-deethylase was elevated 19-fold, benzo(a)pyrene 3-hydroxylase 6-fold, aniline hydroxylase 3-fold, and aminopyrine N-demethylase and uridine diphosphate glucuronyl transferase 2-fold. There was no change in reduced glutathione S-transferase activity. Renal mixed-function oxidase activities were also elevated. Herring gull livers contained very low levels of DT-diaphorase activity which was inducible 3- to 5-fold by oil administration.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0013-9351
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
248-55
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3967642-Administration, Oral,
pubmed-meshheading:3967642-Animals,
pubmed-meshheading:3967642-Birds,
pubmed-meshheading:3967642-Cytochromes,
pubmed-meshheading:3967642-Enzyme Activation,
pubmed-meshheading:3967642-Fuel Oils,
pubmed-meshheading:3967642-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:3967642-Kidney,
pubmed-meshheading:3967642-Microsomes, Liver,
pubmed-meshheading:3967642-Mixed Function Oxygenases,
pubmed-meshheading:3967642-Petroleum,
pubmed-meshheading:3967642-Transferases
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pubmed:year |
1985
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pubmed:articleTitle |
Effects of ingestion of hibernia and Prudhoe Bay crude oils on hepatic and renal mixed function oxidase in nestling herring gulls (Larus argentatus).
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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