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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1986-5-22
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pubmed:abstractText |
To determine the possible role of Branhamella (formerly Neisseria) catarrhalis as a respiratory pathogen, we screened quality sputa (defined by cellular criteria) that showed numerous gram-negative cocci on Gram's stain for the presence of B catarrhalis. In an eight-month period, 52 isolates of B catarrhalis were identified in adults attending a hospital for chest diseases. During this period B catarrhalis was the third most common potential pathogen isolated from sputa. Twenty-two patients (42%) had associated patchy bronchopneumonic or lobar infiltrates. All had negative blood cultures and a generally mild clinical course. The majority of strains (73%) of B catarrhalis produced beta-lactamase and were resistant to penicillin and ampicillin. Isolates (including beta-lactamase-producing strains) were susceptible to erythromycin, tetracycline, and trimethoprim-sulfamethoxazole. These studies demonstrate that in patients with chronic lung disease, the presence of B catarrhalis in sputum can be suspected on the basis of a Gram's stain and may be associated with the development of new pneumonic infiltrates. Since these organisms frequently produce beta-lactamase, empiric antimicrobial therapy should include agents other than the penicillins.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-9926
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
890-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3963981-Aged,
pubmed-meshheading:3963981-Bacterial Infections,
pubmed-meshheading:3963981-Female,
pubmed-meshheading:3963981-Humans,
pubmed-meshheading:3963981-Lung Diseases, Obstructive,
pubmed-meshheading:3963981-Male,
pubmed-meshheading:3963981-Middle Aged,
pubmed-meshheading:3963981-Neisseriaceae,
pubmed-meshheading:3963981-Pneumonia,
pubmed-meshheading:3963981-Respiratory Tract Infections,
pubmed-meshheading:3963981-Sputum
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pubmed:year |
1986
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pubmed:articleTitle |
Branhamella catarrhalis as a lower respiratory tract pathogen in patients with chronic lung disease.
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pubmed:publicationType |
Journal Article
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