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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-5-7
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pubmed:abstractText |
The presence and distribution of gamma-aminobutyric acid (GABA) degradative enzyme (GABA transaminase-succinic semialdehyde dehydrogenase) activity in the rat myenteric plexus was determined histochemically using laminar preparations of the small intestine. Blue-diformazan staining resulting from reduction of the tetrazolium salt, Nitro-BT, during GABA catabolism was present in a scattered population of ileal and jejunal myenteric ganglion cells, including those resembling multipolar type II and unipolar nerve cells. Such staining was almost completely prevented under conditions of GABA-T inhibition. These results indicate that GABA is enzymically degraded at specific sites in the rat enteric nervous system where it is proposed to have a neurotransmitter function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-Aminobutyrate Transaminase,
http://linkedlifedata.com/resource/pubmed/chemical/Aldehyde Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/Aldh5a1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Succinate-Semialdehyde Dehydrogenase
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-90
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:3960392-4-Aminobutyrate Transaminase,
pubmed-meshheading:3960392-Aldehyde Oxidoreductases,
pubmed-meshheading:3960392-Animals,
pubmed-meshheading:3960392-Histocytochemistry,
pubmed-meshheading:3960392-Myenteric Plexus,
pubmed-meshheading:3960392-Rats,
pubmed-meshheading:3960392-Rats, Inbred Strains,
pubmed-meshheading:3960392-Succinate-Semialdehyde Dehydrogenase
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pubmed:year |
1986
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pubmed:articleTitle |
The distribution of GABA-transaminase-dehydrogenase activity in the myenteric plexus of rat small intestine: a histochemical analysis.
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pubmed:publicationType |
Journal Article
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