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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0011847,
umls-concept:C0024518,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0037993,
umls-concept:C0443252,
umls-concept:C0443288,
umls-concept:C0546816,
umls-concept:C1549003,
umls-concept:C1708528,
umls-concept:C1879316
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pubmed:issue |
4
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pubmed:dateCreated |
1986-5-14
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pubmed:abstractText |
We report that transfusions of RT1u Wistar-Furth (WF) spleen cells prevented spontaneous diabetes in the RT1u BB/W rat while RT1b Buffalo rat spleen cells did not. In addition, donor origin WF T lymphocytes were detected in nondiabetic-susceptible BB/W recipients 5 mo after transfusion. Survival of donor-origin lymphocytes may provide the cellular mechanism by which major histocompatibility complex-compatible WF spleen cell transfusions prevent BB rat diabetes.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-14120532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-3079605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-320072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6193172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6343484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6370763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6610693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6759247,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6823559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6836309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6839196,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6974111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-6978807,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-7006928,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-7026724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3958191-7047269
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-9738
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1399-401
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3958191-Animals,
pubmed-meshheading:3958191-Cell Survival,
pubmed-meshheading:3958191-Diabetes Mellitus, Experimental,
pubmed-meshheading:3958191-Major Histocompatibility Complex,
pubmed-meshheading:3958191-Rats,
pubmed-meshheading:3958191-Rats, Inbred BUF,
pubmed-meshheading:3958191-Rats, Inbred Strains,
pubmed-meshheading:3958191-Spleen,
pubmed-meshheading:3958191-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells.
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pubmed:publicationType |
Journal Article
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