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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-4-24
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pubmed:abstractText |
The stability of phenobarbital sodium diluted to 10 mg/mL in 0.9% sodium chloride injection was studied at an unadjusted pH (8.5) and an adjusted pH (10.0) at 4 degrees C over a four-week period. The phenobarbital concentrations were measured before dilution and at 1, 2, 3, 7, 14, and 28 days using high-performance liquid chromatography. The observed phenobarbital concentrations ranged from 98.0 to 106.0% of initial concentration at the unadjusted pH and from 96.7 to 108.5% of initial concentration at the adjusted pH. The diluted phenobarbital sodium was stable over a four-week period at 4 degrees C without the need for pH adjustment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9289
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
384-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3953601-Drug Stability,
pubmed-meshheading:3953601-Humans,
pubmed-meshheading:3953601-Hydrogen-Ion Concentration,
pubmed-meshheading:3953601-Infant,
pubmed-meshheading:3953601-Injections,
pubmed-meshheading:3953601-Phenobarbital,
pubmed-meshheading:3953601-Sodium Chloride,
pubmed-meshheading:3953601-Solutions,
pubmed-meshheading:3953601-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Stability of phenobarbital sodium diluted in 0.9% sodium chloride injection.
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pubmed:publicationType |
Journal Article
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