Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1986-4-10
|
| pubmed:abstractText |
We identified a group of 93 patients (102 eyes) with involutional macular thinning which is a condition that predisposes the affected eyes to developing idiopathic macular holes. The fovea in these patients shows specific architectural changes that can be identified on ophthalmoscopy. On follow-up (mean, 50 months), 26 eyes (27%) developed a macular hole compared to 0% in normal fellow eyes (P less than 0.00001). Patients with pigment epithelial window defects on fluorescein angiography (12 of 15 eyes or 80%), or with no posterior vitreous detachment (15 of 34 eyes or 44%) had the highest risk of developing macular holes. There were seven eyes with involutional macular thinning, pigment epithelial window defects on fluorescein angiography and no posterior vitreous detachment; six (86%) developed a macular hole. Macular degeneration, estrogen supplements, cystoid changes (with normal fluorescein angiography), and poor visual acuity did not increase risk. We present a theory for the pathogenesis of idiopathic macular holes.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0161-6420
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
93
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
153-61
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3951821-Adult,
pubmed-meshheading:3951821-Aged,
pubmed-meshheading:3951821-Choroid,
pubmed-meshheading:3951821-Cysts,
pubmed-meshheading:3951821-Female,
pubmed-meshheading:3951821-Fluorescein Angiography,
pubmed-meshheading:3951821-Follow-Up Studies,
pubmed-meshheading:3951821-Fundus Oculi,
pubmed-meshheading:3951821-Humans,
pubmed-meshheading:3951821-Macula Lutea,
pubmed-meshheading:3951821-Macular Degeneration,
pubmed-meshheading:3951821-Male,
pubmed-meshheading:3951821-Middle Aged,
pubmed-meshheading:3951821-Ophthalmoscopy,
pubmed-meshheading:3951821-Retinal Diseases,
pubmed-meshheading:3951821-Retinal Perforations,
pubmed-meshheading:3951821-Risk,
pubmed-meshheading:3951821-Visual Acuity,
pubmed-meshheading:3951821-Vitreous Body
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Involutional macular thinning. A pre-macular hole condition.
|
| pubmed:publicationType |
Journal Article
|