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pubmed:abstractText |
It was shown that dipyridamole and papaverine induce concentration-dependent inhibition of the absorption of [14C] adenosine by thymocytes. This action is different in lymphocytes from different lymphoid organs and blood. Dipyridamole enhances the effect of various papaverine concentrations on the absorption of adenosine by thymocytes, but it does not exceed the maximal effect, achieved by the latter in high doses. It is supposed, that dipyridamole inhibits the cell transport of adenosine and papaverine influences the adenine-nucleotide metabolism.
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