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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-2-28
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pubmed:abstractText |
Between 1 January 1981 and 1 December 1984, 34 of 396 patients with the acquired immunodeficiency syndrome (AIDS) developed cryptococcal infections. Twenty-six cases are reviewed. Twenty-two patients had brain or meningeal disease; the others had pulmonary disease (2 patients), pericarditis (1 patient), and antigenemia (1 patient). During treatment, 3 patients died of cryptococcosis and 3 died of other causes. Fifteen patients were followed for more than 6 weeks after treatment. Of 8 patients who received no additional amphotericin B, 4 had relapses and died of cryptococcosis within 6 months, 3 died of other causes, and 1 survived. Of 7 patients who received maintenance therapy with amphotericin B, none had relapses, 3 died of other causes, and 4 survived. Our data suggest that maintenance therapy with amphotericin may be needed to prevent relapse in patients with AIDS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
234-40
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3946951-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3946951-Adult,
pubmed-meshheading:3946951-Amphotericin B,
pubmed-meshheading:3946951-Brain Diseases,
pubmed-meshheading:3946951-Cryptococcosis,
pubmed-meshheading:3946951-Drug Therapy, Combination,
pubmed-meshheading:3946951-Female,
pubmed-meshheading:3946951-Flucytosine,
pubmed-meshheading:3946951-Humans,
pubmed-meshheading:3946951-Injections, Intravenous,
pubmed-meshheading:3946951-Injections, Intraventricular,
pubmed-meshheading:3946951-Male,
pubmed-meshheading:3946951-Meningitis,
pubmed-meshheading:3946951-Middle Aged,
pubmed-meshheading:3946951-Prognosis,
pubmed-meshheading:3946951-Recurrence,
pubmed-meshheading:3946951-Retrospective Studies,
pubmed-meshheading:3946951-Tomography, X-Ray Computed
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pubmed:year |
1986
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pubmed:articleTitle |
Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment.
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pubmed:publicationType |
Journal Article
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