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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-2-24
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pubmed:abstractText |
The aim of this study was to detect and identify major low molecular weight (less than 10,000) copper-binding ligands in human bile. Modified gel chromatography was used as the method of ligand detection because it ensures the detection of labile as well as inert metal-ligand complexes. Conjugated bilirubin, peptides, and amino acids, primarily glycine, were isolated as the major ligands. In contrast to the other copper-binding ligands, the peptides were poor zinc binders, suggesting the possibility that they may confer necessary specificity to trace metal elimination.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0037-9727
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
181
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
249-55
|
pubmed:dateRevised |
2007-11-2
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pubmed:meshHeading |
pubmed-meshheading:3945633-Amino Acids,
pubmed-meshheading:3945633-Bile,
pubmed-meshheading:3945633-Chromatography, Gel,
pubmed-meshheading:3945633-Chromatography, Thin Layer,
pubmed-meshheading:3945633-Copper,
pubmed-meshheading:3945633-Humans,
pubmed-meshheading:3945633-Ligands,
pubmed-meshheading:3945633-Molecular Weight,
pubmed-meshheading:3945633-Zinc
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pubmed:year |
1986
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pubmed:articleTitle |
Low molecular weight copper-binding ligands in human bile.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, Non-P.H.S.
|