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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1979-11-21
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pubmed:abstractText |
In native, heated or otherwise treated egg white and in sera of men and guinea pigs, haemagglutination inhibition titres were determined against three inhibitor-sensitive (IS) strains and one inhibitor-resistant (IR) variant on influenza A virus. A few human sera with no detectable antibody revealed high inhibition titres even against the IR variant. Human sera after treatment with trypsin and periodate revealed mostly a reduction or no change, and exceptionally an increase of their inhibition titre. The extent of these changes varied with different influenza virus strains and showed a positive correlation with the inhibitor content and no correlation with the antibody levels of the sera. The so-called "nonspecific" thermostable inhibitors possess a certain degree of specificity for different influenza virus strains.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0001-723X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:39434-Animals,
pubmed-meshheading:39434-Antibodies, Viral,
pubmed-meshheading:39434-Antiviral Agents,
pubmed-meshheading:39434-Female,
pubmed-meshheading:39434-Genetic Variation,
pubmed-meshheading:39434-Guinea Pigs,
pubmed-meshheading:39434-Hemagglutination Inhibition Tests,
pubmed-meshheading:39434-Hot Temperature,
pubmed-meshheading:39434-Humans,
pubmed-meshheading:39434-Influenza A virus,
pubmed-meshheading:39434-Male,
pubmed-meshheading:39434-Periodic Acid,
pubmed-meshheading:39434-Trypsin
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pubmed:year |
1979
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pubmed:articleTitle |
Detection of "alpha-type" inhibitors in the presence of low levels of specific influenza antibodies.
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pubmed:publicationType |
Journal Article
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