Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-2-20
pubmed:abstractText
With the discovery of new and pharmacologically better described agents, the pursuit of a method for the enhancement of nonspecific host defense against bacterial infection has received a new infusion of interest. Work with the synthetic glycopeptide muramyl dipeptide has indicated its usefulness in a variety of surgically simulated illnesses in experimental animals. The extent of that work is described in detail and current mechanisms of action are explored that focus on the release of transmitter substances from the macrophage, the immediate impact on acute inflammatory cells, and an organ-by-organ dissection of the animal suggesting enhanced containment of experimental infection in animals treated with muramyl dipeptide.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The enhancement of host defenses against infection--search for the Holy Grail?
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't