Linked Life Data

3939489

Source:http://linkedlifedata.com/resource/pubmed/id/3939489

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1986-12-17
pubmed:abstractText
A simple procedure for identifying amyloid fibril proteins in biopsies and small tissue fragments is described. Amyloid fibrils from 21 patients with amyloid deposits (including 6 controls) were freed from soluble proteins and concentrated by a microextraction technique. The solubilized amyloid fibril proteins were then examined by immunodiffusion with antisera directed against amyloid fibril proteins (AA, A lambda, A kappa, ASc1, AF), cystatin C and beta 2-microglobulin. 9 out of 11 specimens with inconclusive immunohistochemical results, 5 other specimens, and 6 control specimens could clearly be typed with this method. Microextraction followed by immunochemical identification, therefore, can be considered an additional option for chemical amyloid classification in those cases in which immunohistochemical typing does not yield unequivocal results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0252-1172
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
18-28
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Immunochemical typing of amyloid deposits after microextraction from biopsies.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't