Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1986-6-2
pubmed:abstractText
The serum SHGB (sex-hormone-binding globulin) concentration was measured in patients with secondary amenorrhea in order to determine its role in the regulation of androgen and estrogen metabolism in the course of the normal and irregular menstrual cycle. SHBG concentration was lower than in the control group in 52% of amenorrheic patients, but this difference was not statistically significant due to great individual variations. If the patients were divided in 2 groups according to Prolactin (PRL) concentration, significant decrease in SHGB concentration was observed in the group with elevated PRL concentrations. Correlation of SHBG with estrogen (E2), testosterone (T), progesterone (PRG) and PRL was tested and results show the weak correlation (r = 0.4) between SHGB and T and more significant correlation between SHGB and E2 in the group with basal E2 concentration below 100 pmol/1. SHGB test should be included in the evaluation of alterations of androgen and estrogen metabolism.
pubmed:language
hrv
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0352-5562
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-5
pubmed:dateRevised
2009-11-9
pubmed:meshHeading
pubmed:articleTitle
[Determination of the concentration of sex hormone-binding globulin in the clinical evaluation of women with secondary amenorrhea].
pubmed:publicationType
Journal Article, English Abstract