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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1980-4-17
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pubmed:abstractText |
Several groups of streptococci were tested for production of pyrogenic exotoxins (SPE) with Ouchterlony immunodiffusion, a newly developed passive hemagglutination inhibition assay, and an assay for pyrogenicity and capacity to enhance lethal endotoxin shock. With use of these assays, 68 (91%) of 75 group A streptococcal strains were positive for one or more of SPE types A, B, and C; seven were negative for both the known SPE types and antigenically unrelated pyrogenic exotoxins. Group A strains producing both SPE B and C were the most common, and strains producing A alone or AB and AC together were the least common. All of 11 rheumatogenic group A streptococci elaborated SPE C either alone or together with one or both of SPE types A and B. The 10 nephritogenic strains tested were positive for SPE B; five were positive for B alone. In contrast to group A streptococci, non-group A strains (41 tested) did not produce the known SPE types, and 19 of 19 tested were negative for antigenically unrelated pyrogenic exotoxins. Group A strains from Holland, India, and Japan also elaborated SPE. Several group A streptococci used widely in laboratory experiments were tested for SPE types produced.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
676-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:393776-Animals,
pubmed-meshheading:393776-Cardiomyopathies,
pubmed-meshheading:393776-Exotoxins,
pubmed-meshheading:393776-Hemagglutination Inhibition Tests,
pubmed-meshheading:393776-Humans,
pubmed-meshheading:393776-Nephritis,
pubmed-meshheading:393776-Pyrogens,
pubmed-meshheading:393776-Rabbits,
pubmed-meshheading:393776-Rheumatic Diseases,
pubmed-meshheading:393776-Shock, Septic,
pubmed-meshheading:393776-Streptococcus agalactiae,
pubmed-meshheading:393776-Streptococcus pyogenes
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pubmed:year |
1979
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pubmed:articleTitle |
Production of pyrogenic exotoxin by groups of streptococci: association with group A.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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