Linked Life Data

3935621

Source:http://linkedlifedata.com/resource/pubmed/id/3935621

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1986-2-20
pubmed:abstractText
Sarcophaga lectin, a lectin purified from the hemolymph of Sarcophaga peregrina (flesh fly) larvae, was found to be therapeutically effective against both ascitic and solid tumors. It was especially effective when injected directly into or around nodules of the syngeneic tumor Meth A transplanted intradermally into BALB/c mice. It also induced cytotoxic activity against L-929 cells when it was added to the culture medium of macrophages in vitro. Similar cytotoxic activity was detected transiently in the serum when it was injected into the abdominal cavity of mice, in which sarcoma 180 cells had been inoculated. Probably, this cytotoxic activity induced by Sarcophaga lectin partly contributes to the elimination of tumors. The possible role of this cytotoxic activity is discussed from the viewpoint of ontogeny.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0910-5050
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1027-33
pubmed:dateRevised
2005-10-19
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Antitumor effect of Sarcophaga lectin on murine transplanted tumors.
pubmed:publicationType
Journal Article