Linked Life Data

3930826

Source:http://linkedlifedata.com/resource/pubmed/id/3930826

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-11-15
pubmed:abstractText
Retinal excitation implies transmembrane ion movement in the retinal neurones. In order to maintain excitability, the neurones utilize energy derived from the hydrolysis of ATP. ATP is produced in the mitochondria, which consume O2 and carbohydrates for this purpose. Thus, O2 consumption is essential for maintaining ATP in the retinal neurons and, therefore, for maintaining excitability. O2 is delivered to the retinal mitochondria by the microcirculation, where variations of the blood flow cause dramatic fluctuations in the local PO2 in the tissue. The retinal blood flow can be impaired by experimental changes in the pH of the glial cells surrounding the arterioles. According to a hypothesis, intraglial pH modulates the release of a mediator (prostaglandins) which in turn acts on the smooth musculature of the arteriole wall and thus controls vascular motility.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0023-2165
pubmed:author
pubmed:issnType
Print
pubmed:volume
186
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
477-9
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Various aspects of the existing relationship between retinal neuronal function, oxidative metabolism and the constant O2 supply by the microcirculation].
pubmed:publicationType
Journal Article, English Abstract