Linked Life Data

3928340

Source:http://linkedlifedata.com/resource/pubmed/id/3928340

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-10-21
pubmed:abstractText
Growth hormone-releasing factor-like immunoreactivity (GRF-LI) was detected in partially purified extracts of rat hypothalamus and duodenum with a highly specific RIA for rat GRF (rGRF). The concentration of rGRF-LI in the rat hypothalamus was 32.5 fmol/mg dry weight (455 fmol or 3.18 ng/region), while the rat duodenum contained 2.15 fmol/mg dry weight (111 fmol or 0.78 ng/region). Partially purified hypothalamic and duodenal extracts exhibited displacement of the tracer parallel to rGRF. GRF-LI levels in all other brain regions (brainstem, cortex) or gastrointestinal tract tissues (forestomach, antrum, ileum, colon, pancreas) measured were close to the detection level of the RIA. rGRF-LI in hypothalamic and duodenal extracts behaved like synthetic rGRF in both gel filtration and reverse-phase HPLC systems. Coelution of rGRF-LI contained in both these tissue extracts with synthetic rGRF suggests that these molecules are similar, if not identical.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
117
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1710-2
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Presence of growth hormone-releasing factor-like immunoreactivity in rat duodenum.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't