Linked Life Data

3925753

Source:http://linkedlifedata.com/resource/pubmed/id/3925753

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-8-7
pubmed:abstractText
Factor VIII von Willebrand may be detected by a Ristocetin-dependent platelet agglutination reaction. The authors have measured plasma levels of Factor VIII-related Ristocetin cofactor (VIIIR:RCoF) using formalin-fixed platelets tested by an aggregometric method or by a new, commercially available glass slide test. Plasmas were obtained from patients with von Willebrand's disease and Cushing's syndrome, and from normal controls. Von Willebrand factor (vWf) levels varied between 0-500% of the normal. A good correlation (r = 0.95) was found comparing the results obtained by the two methods over the entire range. If all patients were considered, a satisfactory correlation was obtained between VIIIR:RCoF and VIII-related antigen (VIIIR:Ag), both by the aggregometric method (r = 0.79) and by the glass slide method (r = 0.88). On the contrary, if values below 25% of the normal are taken into account, only a mild correlation was found between VIIIR: RCoF (aggregometric method) and VIIIR:Ag and no correlation between VIIIR:RCoF (glass slide method) and VIIIR:Ag. No correlation, regardless of the method used, was found between VIIIR:RCoF and VIIIR:Ag for values above 120%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-11
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The evaluation of factor VIII antigen by means of a simple slide test.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't