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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1985-7-29
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pubmed:abstractText |
Thrombin-induced platelet malondialdehyde (MDA) formation and plasma malondialdehyde-like material (MDA-LM) were evaluated in 12 healthy subjects before and after 1 and 7 days from aspirin (1 g) ingestion. 24 hr after aspirin administration, platelet MDA was almost abolished while MDA-LM showed a 23% decrease. Platelet MDA and plasma MDA-LM returned to baseline values 7 days after aspirin ingestion. These data suggest that platelet cyclooxygenase pathway affects only in part plasma MDA-LM. The evaluation of plasma MDA-LM before and after aspirin could be useful for evaluating in vivo platelet cyclooxygenase activation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0024-4201
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
322-4
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:3925272-Adult,
pubmed-meshheading:3925272-Aspirin,
pubmed-meshheading:3925272-Blood Platelets,
pubmed-meshheading:3925272-Female,
pubmed-meshheading:3925272-Humans,
pubmed-meshheading:3925272-Kinetics,
pubmed-meshheading:3925272-Male,
pubmed-meshheading:3925272-Malonates,
pubmed-meshheading:3925272-Malondialdehyde,
pubmed-meshheading:3925272-Prostaglandin-Endoperoxide Synthases
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pubmed:year |
1985
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pubmed:articleTitle |
Relationship between platelet cyclooxygenase pathway and plasma malondialdehyde-like material.
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pubmed:publicationType |
Journal Article
|