Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1980-3-17
pubmed:abstractText
The phosphoenolpyruvate-dependent phosphotransferase-mediated sugar transport in Escherichia coli is inhibited by the energized of the membrane. This was shown in intact cells as well as in membrane vesicles. Relaxation of the proton gradient by uncouplers stimulated the uptake of sugars via the phosphotransferase system in aerobically cultured cells. No such effect was seen in anaerobic cells, apparently because the cell membrane of these cells is poorly energized. Energization by respiration of D-lactate or ascorbate inhibited the phosphotransferase uptake system in membrane vesicles. This inhibition was reversed by the addition of cyanide. Oxamate, a specific inhibitor of lactate dehydrogenase, prevented the inhibitory effect of D-lactate. Membrane vesicles prepared from a cytochrome-less mutant were not energized by D-lactate oxidation and the phosphotransferase uptake system was not inhibited.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-1091634, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-1103128, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-124171, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-133025, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-13618272, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-14907713, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-209727, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-339892, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4264299, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4278547, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4297266, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4351530, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4609121, http://linkedlifedata.com/resource/pubmed/commentcorrection/392504-4872728
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5529-33
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Control of phosphoenolpyruvate-dependent phosphotransferase-mediated sugar transport in Escherichia coli by energization of the cell membrane.
pubmed:publicationType
Journal Article