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pubmed-article:3923343pubmed:abstractTextSpontaneous and mutagen-induced sister-chromatid exchange frequencies have been studied in the peripheral blood lymphocytes of 6 patients with motor neurone disease. Their values were compared with those obtained in age- and sex-matched healthy controls. No significant differences were observed between the 2 groups. These results do not support the hypothesis of a defect in the repair of DNA damage as the primary abnormality in the development of the disease.lld:pubmed
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pubmed-article:3923343pubmed:articleTitleSpontaneous and mutagen-induced sister chromatid exchange in motor neurone disease.lld:pubmed
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