Linked Life Data

3922604

Source:http://linkedlifedata.com/resource/pubmed/id/3922604

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-7-9
pubmed:abstractText
A homogeneous form of pig interleukin 1 (catabolin) stimulates the resorption of mouse bones in culture. Concentrations as low as 25 pM are effective, demonstrating that it is more potent than 1,25-dihydroxy-vitamin D3 in our assay system. Catabolin was originally defined by its ability to stimulate glycosaminoglycan release from cartilage in culture and purified from pig mononuclear leucocyte supernatants. It also augments lectin-induced thymocyte proliferation, indicating that it is a form of pig interleukin 1. Bone resorbing factors are synthesized by other cell types, including fibroblasts and osteoblasts; we suggest that such cytokines are important in mediating the action of systemic hormones on bone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0171-967X
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
95-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Pig interleukin 1 (catabolin) is a potent stimulator of bone resorption in vitro.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't