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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1985-6-10
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pubmed:abstractText |
The level of circulating antibody to phenolic glycolipid I of Mycobacterium leprae was determined in 18 inbred strains of mice after immunization with M. leprae organisms. By using a solid-phase radioimmunoassay with phenolic glycolipid I as test antigen, a continuous distribution of antibody levels ranging from high to low was observed. The level was found to be controlled by multiple genes, including both H-2 complex- and Igh allotype complex-linked genes. Low antibody response to phenolic glycolipid I was shown to be inherited as a dominant trait in three combinations of high X low responder F1 progeny.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-1176777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-1194855,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-1194856,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-152980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-158056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-16557927,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-396427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4105537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4121713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4360861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4460870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4583777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-46644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4825243,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-4898388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-5765335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-5796860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6184369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6193065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6339369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6348948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6360898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6362932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6366573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6407793,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6454034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-659858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6749710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6754640,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-6997379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-7009448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-7024248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-7025147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-7452002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-77549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-79606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3921463-965768
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
474-9
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:3921463-Animals,
pubmed-meshheading:3921463-Antibodies, Bacterial,
pubmed-meshheading:3921463-Antigens, Bacterial,
pubmed-meshheading:3921463-Crosses, Genetic,
pubmed-meshheading:3921463-Female,
pubmed-meshheading:3921463-Genes, Dominant,
pubmed-meshheading:3921463-Genes, MHC Class II,
pubmed-meshheading:3921463-Glycolipids,
pubmed-meshheading:3921463-H-2 Antigens,
pubmed-meshheading:3921463-Immunization,
pubmed-meshheading:3921463-Immunoglobulin Allotypes,
pubmed-meshheading:3921463-Immunoglobulin G,
pubmed-meshheading:3921463-Immunoglobulin Heavy Chains,
pubmed-meshheading:3921463-Mice,
pubmed-meshheading:3921463-Mice, Inbred Strains,
pubmed-meshheading:3921463-Mycobacterium leprae,
pubmed-meshheading:3921463-Radioimmunoassay,
pubmed-meshheading:3921463-Species Specificity
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pubmed:year |
1985
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pubmed:articleTitle |
Antibody response to phenolic glycolipid I in inbred mice immunized with Mycobacterium leprae.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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