|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1985-6-17
|
|
pubmed:abstractText |
Phosphoprotein phosphatase inhibitor-2 (i-2) was rapidly isolated from mouse diaphragm extracts by the use of specific antibodies. The i-2 so obtained was associated with ATP-Mg and FA/GSK-3 dependent phosphatase activity, supporting the idea that i-2 is in fact a component of this form of phosphatase. Inhibitor-2 isolated from diaphragms incubated with [32P]phosphate contained both phosphoserine (approximately 90%) and phosphothreonine (approximately 10%). Therefore, i-2 is multiply phosphorylated in mouse diaphragm and the potential exists for control of the ATP-Mg-dependent phosphatase via multiple phosphorylation sites in vivo.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0014-5793
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
22
|
|
pubmed:volume |
183
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
423-9
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:3921407-Adenosine Triphosphate,
pubmed-meshheading:3921407-Amino Acids,
pubmed-meshheading:3921407-Animals,
pubmed-meshheading:3921407-Diaphragm,
pubmed-meshheading:3921407-Immunosorbent Techniques,
pubmed-meshheading:3921407-Male,
pubmed-meshheading:3921407-Mice,
pubmed-meshheading:3921407-Molecular Weight,
pubmed-meshheading:3921407-Muscle Proteins,
pubmed-meshheading:3921407-Muscles,
pubmed-meshheading:3921407-Phosphorylation,
pubmed-meshheading:3921407-Proteins,
pubmed-meshheading:3921407-Serine,
pubmed-meshheading:3921407-Threonine
|
|
pubmed:year |
1985
|
|
pubmed:articleTitle |
Phosphoprotein phosphatase inhibitor-2 is phosphorylated at both serine and threonine residues in mouse diaphragm.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
