Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-4-15
pubmed:abstractText
Macrophage microsomes catalyzed the transfer of arachidonic acid (20:4) from 1,2-diacyl-glycerophosphocholine (GPC) to 1-alkyl-GPC (lyso platelet-activating factor). This enzyme reaction did not require the presence of cofactors such as Co A. Free arachidonic acid or linoleic acid-labeled phospholipids failed to act as the acyl donor. These results suggest that the reaction is a CoA-independent direct transfer of arachidonic acid. This arachidonoyl transacylation system may play a very important role in the metabolism of lyso platelet-activating factor and also in the elimination or release of arachidonic acid from diacyl-GPC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
127
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
384-90
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
CoA-independent transfer of arachidonic acid from 1,2-diacyl-sn-glycero-3-phosphocholine to 1-O-alkyl-sn-glycero-3-phosphocholine (lyso platelet-activating factor) by macrophage microsomes.
pubmed:publicationType
Journal Article