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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1985-3-25
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pubmed:abstractText |
We have mapped the gene encoding the T cell differentiation antigen Leu-2/T8 to human chromosome 2 by hybridization of a Leu-2/T8 complementary DNA clone to DNA from a panel of mouse-human cell hybrids. In situ hybridization further localizes the gene to the 2p1 region in close proximity to the Ig kappa light chain gene. The Leu-2/T8 gene translocates with C kappa to chromosome 8 in a Burkitt lymphoma line carrying a t(2;8) translocation. These data support the hypothesis that Leu-2/T8 is the human homologue of the mouse Lyt-2,3 antigen.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-100557,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-314668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-4547628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-5021438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6165796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6195086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6205976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6286765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6331676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6421984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6424112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6440142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6457863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6494913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6605969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6787593,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6812058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6961453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6978378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6980419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3919142-6981813
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429-34
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:3919142-Animals,
pubmed-meshheading:3919142-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:3919142-Antigens, Surface,
pubmed-meshheading:3919142-Chromosomes, Human, 1-3,
pubmed-meshheading:3919142-Cloning, Molecular,
pubmed-meshheading:3919142-DNA,
pubmed-meshheading:3919142-Genes, MHC Class II,
pubmed-meshheading:3919142-Genetic Code,
pubmed-meshheading:3919142-Genetic Linkage,
pubmed-meshheading:3919142-Humans,
pubmed-meshheading:3919142-Hybrid Cells,
pubmed-meshheading:3919142-Immunoglobulin Light Chains,
pubmed-meshheading:3919142-Immunoglobulin kappa-Chains,
pubmed-meshheading:3919142-Male,
pubmed-meshheading:3919142-Metaphase,
pubmed-meshheading:3919142-Mice
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pubmed:year |
1985
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pubmed:articleTitle |
Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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